
Fluorescence image of osteosarcoma cell
Fluorescence image of osteosarcoma cell with labeled actin cytoskeleton network. The AFM was used to make force measurements on the cell, before and after treatment with a drug that disrupts the actin network. Force curves show a dramatic softening of the cell indicated by the much more gradual increase in force on the treated cell (dotted line) compared to the untreated cell (solid line). Data courtesy of Alexandre Berquand, Andreas Holloschi, and Petra Kioshis, FachHochschule Mannheim, Germany. |